HitPredict

Interactor 1: IL4RA (P24394)
Interleukin-4 receptor subunit alpha (IL-4 receptor subunit alpha) (IL-4R subunit alpha) (IL-4R-alpha) (IL-4RA) (CD antigen CD124) [Cleaved into: Soluble interleukin-4 receptor subunit alpha (Soluble IL-4 receptor subunit alpha) (Soluble IL-4R-alpha) (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)]
Gene: IL4R

Interactor 2: I13R1 (P78552)
Interleukin-13 receptor subunit alpha-1 (IL-13 receptor subunit alpha-1) (IL-13R subunit alpha-1) (IL-13R-alpha-1) (IL-13RA1) (Cancer/testis antigen 19) (CT19) (CD antigen CD213a1)
Gene: IL13RA1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 8910586, 18243101
Identification Methods protein cross-linking with a bifunctional reagent, x-ray crystallography
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004896 - cytokine receptor activity
GO:0005886 - plasma membrane
GO:0009897 - external side of plasma membrane
GO:0019221 - cytokine-mediated signaling pathway
GO:0043235 - receptor complex
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 825
Hs

1 427
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Last updated: 15 Jul 2024