HitPredict

Interactor 1: COT2 (P24468)
COUP transcription factor 2 (COUP-TF2) (Apolipoprotein A-I regulatory protein 1) (ARP-1) (COUP transcription factor II) (COUP-TF II) (Nuclear receptor subfamily 2 group F member 2)
Gene: NR2F2

Interactor 2: KI67 (P46013)
Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67)
Gene: MKI67

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26949251
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 414 Hs			1 3256
+	Hs
		369148 ESR1_HUMAN (1-400): 5.27e-102: 316: 23.01		KI67_HUMAN (1-3256): 0: 1046: 100.00
+	Hs
		801020 NR2C2_HUMAN (68-196): 7.59e-34: 134: 50.00		KI67_HUMAN (1-3256): 0: 1046: 100.00
+	Hs
		369607 ESR1_HUMAN (1-400): 5.27e-102: 316: 23.01		MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14
+	Hs
		369171 ESR1_HUMAN (1-400): 5.27e-102: 316: 23.01		PRC2A_HUMAN (513-2601): 5.1e-21: 104: 7.93
+	Hs
		370728 ESR1_HUMAN (1-400): 5.27e-102: 316: 23.01		SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53
+	Hs
		782571 HNF4A_HUMAN (57-407): 8.83e-112: 337: 34.19		NIPBL_HUMAN (2321-3191): 7.29e-12: 74.4: 12.83
+	Hs
		370105 ESR1_HUMAN (1-400): 5.27e-102: 316: 23.01		TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85
+	Hs
		369815 ESR1_HUMAN (1-400): 5.27e-102: 316: 23.01		NIPBL_HUMAN (2321-3191): 7.29e-12: 74.4: 12.83
+	Hs
		824538 NR2C2_HUMAN (68-196): 7.59e-34: 134: 50.00		SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53
+	Hs
		824108 NR2C2_HUMAN (68-196): 7.59e-34: 134: 50.00		NIPBL_HUMAN (2321-3191): 7.29e-12: 74.4: 12.83