Interactor 1: AKAP5 (P24588)
A-kinase anchor protein 5 (AKAP-5) (A-kinase anchor protein 79 kDa) (AKAP 79) (H21) (cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein)
Gene: AKAP5
Interactor 2: PP2BA (Q08209)
Protein phosphatase 3 catalytic subunit alpha (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin A alpha) (Calmodulin-dependent calcineurin A subunit alpha isoform) (CNA alpha) (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform)
Gene: PPP3CA
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.80 | 0.60 | 0.696 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9765270, 32296183, 22343722, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, fluorescent resonance energy transfer, validated two hybrid, two hybrid array, two hybrid prey pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005516 - calmodulin binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008287 - protein serine/threonine phosphatase complex GO:0033173 - calcineurin-NFAT signaling cascade and 3 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
