HitPredict

Interactor 1: AKAP5 (P24588)
A-kinase anchor protein 5 (AKAP-5) (A-kinase anchor protein 79 kDa) (AKAP 79) (H21) (cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein)
Gene: AKAP5

Interactor 2: TRPV4 (Q9HBA0)
Transient receptor potential cation channel subfamily V member 4 (TrpV4) (Osm-9-like TRP channel 4) (OTRPC4) (Transient receptor potential protein 12) (TRP12) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC)
Gene: TRPV4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18701070
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005516 - calmodulin binding GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 871
+	Hs
		623547 AKAP5_HUMAN (1-427): 0: 545: 100.00		TRPV1_HUMAN (19-841): 0: 603: 43.94
+	Hs
		623560 AKAP5_HUMAN (1-427): 0: 545: 100.00		TRPV2_HUMAN (67-809): 8.28e-165: 500: 42.67
+	Hs
		623548 AKAP5_HUMAN (1-427): 0: 545: 100.00		TRPV3_HUMAN (9-836): 1.63e-154: 474: 37.92
+	Rn
		94058 F1LPP6_RAT (278-427): 8.95e-43: 161: 68.63		TRPV1_RAT (37-841): 0: 603: 45.03
+	Mm
		88322 AKAP5_MOUSE (278-427): 5.49e-42: 159: 69.28		TRPV1_MOUSE (37-841): 0: 603: 44.91
+	Hs
		274703 AKAP5_HUMAN (1-427): 0: 545: 100.00		TRPA1_HUMAN (64-516): 1.17e-36: 151: 10.71