HitPredict

Interactor 1: PAX3 (P24610)
Paired box protein Pax-3
Gene: PAX3

Interactor 2: MEOX2 (P32443)
Homeobox protein MOX-2 (Growth arrest-specific homeobox) (Mesenchyme homeobox 2)
Gene: MEOX2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	20211142
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II and 1 others more... GO:0043565 - sequence-specific DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 479 Mm			1 303
+	Hs
		620236 PAX3_HUMAN (1-479): 3.99e-124: 372: 98.75		MEOX2_HUMAN (1-303): 4.64e-56: 185: 96.71
+	Mm
		192281 PAX3_MOUSE (1-479): 3.27e-125: 374: 100.00		ALX4_MOUSE (8-302): 1.72e-34: 131: 18.35
+	Mm
		623693 PAX3_MOUSE (1-479): 3.27e-125: 374: 100.00		MEOX1_MOUSE (4-269): 8.47e-33: 123: 37.13
+	Hs
		620235 PAX3_HUMAN (1-479): 3.99e-124: 372: 98.75		MEOX1_HUMAN (4-269): 4.24e-29: 113: 37.23
+	Hs
		620134 PAX7_HUMAN (1-475): 1.32e-112: 343: 73.47		MNX1_HUMAN (179-252): 1.37e-14: 75.5: 54.05
+	Hs
		620171 PAX7_HUMAN (1-475): 1.32e-112: 343: 73.47		ZFHX4_HUMAN (123-256): 9.85e-12: 67.7: 16.42
+	Ce
		106229 VAB3_CAEEL (31-463): 2.29e-70: 232: 31.53		MEC3_CAEEL (31-263): 8.78e-34: 127: 20.54
+	Dm
		447432 GSBN_DROME (30-395): 1.36e-63: 214: 45.90		UBX_DROME (37-247): 2.28e-29: 116: 24.19
+	Ce
		105793 PAX3H_CAEEL (28-317): 2.18e-60: 202: 41.72		MEC3_CAEEL (31-263): 8.78e-34: 127: 20.54
+	Mm
		453073 PAX6_MOUSE (32-411): 8.11e-64: 214: 36.72		HXA9_MOUSE (24-252): 1.04e-29: 115: 26.03
+	Hs
		641345 PAX6_HUMAN (32-411): 8.11e-64: 214: 36.72		MNX1_HUMAN (179-252): 1.37e-14: 75.5: 54.05
+	Mm
		192304 Q8VD35_MOUSE (213-399): 7.93e-44: 157: 32.86		ALX4_MOUSE (8-302): 1.72e-34: 131: 18.35
+	Mm
		192303 Q8R0B5_MOUSE (185-399): 2.43e-43: 156: 30.29		ALX4_MOUSE (8-302): 1.72e-34: 131: 18.35
+	Hs
		641468 PAX6_HUMAN (32-411): 8.11e-64: 214: 36.72		ZFHX4_HUMAN (123-256): 9.85e-12: 67.7: 16.42
+	Ce
		105794 PAX3H_CAEEL (28-317): 2.18e-60: 202: 41.72		LIN39_CAEEL (187-243): 3.08e-14: 72.8: 63.16
+	Hs
		567834 PAX8_HUMAN (27-479): 8.21e-39: 148: 28.69		HXB9_HUMAN (14-251): 2.27e-30: 116: 23.53
+	Hs
		973860 PAX2_HUMAN (32-358): 5.75e-45: 164: 34.31		ZFHX4_HUMAN (123-256): 9.85e-12: 67.7: 16.42
+	Hs
		837763 PAX8_HUMAN (27-479): 8.21e-39: 148: 28.69		MNX1_HUMAN (179-252): 1.37e-14: 75.5: 54.05
+	Dm
		447322 POXM_DROME (27-171): 3.3e-39: 147: 64.14		SCR_DROME (176-243): 2.05e-13: 72: 54.41
+	Hs
		988779 PAX8_HUMAN (27-479): 8.21e-39: 148: 28.69		ZFHX4_HUMAN (123-256): 9.85e-12: 67.7: 16.42