HitPredict

Interactor 1: PAX3 (P24610)
Paired box protein Pax-3
Gene: PAX3

Interactor 2: TLE4 (Q62441)
Transducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4)
Gene: TLE4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15729346
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005667 - transcription regulator complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 479 Mm			1 773
+	Hs
		620144 PAX7_HUMAN (1-475): 1.32e-112: 343: 73.47		TLE4_HUMAN (1-773): 0: 606: 99.61
+	Hs
		620142 PAX7_HUMAN (1-475): 1.32e-112: 343: 73.47		TLE1_HUMAN (8-773): 0: 565: 86.27
+	Hs
		620143 PAX7_HUMAN (1-475): 1.32e-112: 343: 73.47		TLE3_HUMAN (8-773): 1.08e-178: 532: 81.29
+	Hs
		641379 PAX6_HUMAN (32-411): 8.11e-64: 214: 36.72		TLE4_HUMAN (1-773): 0: 606: 99.61
+	Hs
		641377 PAX6_HUMAN (32-411): 8.11e-64: 214: 36.72		TLE1_HUMAN (8-773): 0: 565: 86.27
+	Hs
		971652 PAX5_HUMAN (25-376): 1.6e-47: 170: 35.29		TLE4_HUMAN (1-773): 0: 606: 99.61
+	Hs
		980927 PAX8_HUMAN (27-479): 8.21e-39: 148: 28.69		TLE4_HUMAN (1-773): 0: 606: 99.61
+	Hs
		641378 PAX6_HUMAN (32-411): 8.11e-64: 214: 36.72		TLE3_HUMAN (8-773): 1.08e-178: 532: 81.29
+	Hs
		973842 PAX2_HUMAN (32-358): 5.75e-45: 164: 34.31		TLE1_HUMAN (8-773): 0: 565: 86.27
+	Hs
		980588 PAX8_HUMAN (27-479): 8.21e-39: 148: 28.69		TLE1_HUMAN (8-773): 0: 565: 86.27
+	Hs
		973843 PAX2_HUMAN (32-358): 5.75e-45: 164: 34.31		TLE3_HUMAN (8-773): 1.08e-178: 532: 81.29
+	Hs
		980733 PAX8_HUMAN (27-479): 8.21e-39: 148: 28.69		TLE3_HUMAN (8-773): 1.08e-178: 532: 81.29
+	Hs
		620146 PAX7_HUMAN (1-475): 1.32e-112: 343: 73.47		TLE5_HUMAN (8-205): 5.29e-93: 290: 67.68
+	Hs
		245559 PAX7_HUMAN (1-475): 1.32e-112: 343: 73.47		TBL1X_HUMAN (572-772): 7.1e-46: 175: 15.60
+	Ce
		105784 PAX3H_CAEEL (28-317): 2.18e-60: 202: 41.72		UNC37_CAEEL (24-773): 1.2e-92: 304: 36.86
+	Hs
		641385 PAX6_HUMAN (32-411): 8.11e-64: 214: 36.72		TLE5_HUMAN (8-205): 5.29e-93: 290: 67.68
+	Hs
		620138 PAX7_HUMAN (1-475): 1.32e-112: 343: 73.47		WDR5_HUMAN (658-772): 1.3e-35: 139: 21.37
+	Hs
		973846 PAX2_HUMAN (32-358): 5.75e-45: 164: 34.31		TLE5_HUMAN (8-205): 5.29e-93: 290: 67.68
+	Hs
		988754 PAX8_HUMAN (27-479): 8.21e-39: 148: 28.69		TLE5_HUMAN (8-205): 5.29e-93: 290: 67.68
+	Hs
		245563 PAX6_HUMAN (32-411): 8.11e-64: 214: 36.72		TBL1X_HUMAN (572-772): 7.1e-46: 175: 15.60