HitPredict

Interactor 1: PPAC (P24666)
Low molecular weight phosphotyrosine protein phosphatase (LMW-PTP) (LMW-PTPase) (EC 3.1.3.48) (Adipocyte acid phosphatase) (Low molecular weight cytosolic acid phosphatase) (EC 3.1.3.2) (Red cell acid phosphatase 1)
Gene: ACP1

Interactor 2: TNK1 (Q13470)
Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)
Gene: TNK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 158 Hs			1 666
+	Hs
		383617 PPAC_HUMAN (1-158): 8.34e-88: 254: 100.00		ERBB2_HUMAN (65-631): 7.95e-122: 393: 22.82
+	Hs
		623729 PPAC_HUMAN (1-158): 8.34e-88: 254: 100.00		EPHB1_HUMAN (69-405): 4.02e-119: 380: 30.29
+	Hs
		623718 PPAC_HUMAN (1-158): 8.34e-88: 254: 100.00		EPHA2_HUMAN (64-447): 1.01e-108: 352: 27.74
+	Hs
		337951 PPAC_HUMAN (1-158): 8.34e-88: 254: 100.00		EGFR_HUMAN (89-373): 4.38e-46: 178: 36.59