Interactor 1: THIL (P24752)
Acetyl-CoA acetyltransferase, mitochondrial (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) (T2)
Gene: ACAT1

Interactor 2: THIC (Q9BWD1)
Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase)
Gene: ACAT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 26186194, 28514442
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Thiolase_C~Thiolase_C, Thiolase_C~Thiolase_N, Thiolase_N~Thiolase_N
Common GO terms GO:0003985 - acetyl-CoA C-acetyltransferase activity
GO:0005739 - mitochondrion
GO:0006635 - fatty acid beta-oxidation
GO:0070062 - extracellular exosome
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 427
Hs

1 397
+ Hs
+ Hs
+ At
+ Ec
+ Sc
+ Sc
+ Mt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024