HitPredict

Interactor 1: CG22 (P24869)
G2/mitotic-specific cyclin-2
Gene: CLB2

Interactor 2: CDC20 (P26309)
APC/C activator protein CDC20 (Cell division control protein 20)
Gene: CDC20

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	11562348, 14743219, 12574115
Identification Methods	coimmunoprecipitation, affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 491 Sc			1 610
+	Sc
		624704 CG22_YEAST (1-491): 7.09e-157: 456: 100.00		CDH1_YEAST (111-557): 2.02e-98: 313: 28.76
+	Sc
		624660 CG21_YEAST (7-491): 4.16e-105: 323: 55.33		AMA1_YEAST (172-558): 6.88e-102: 322: 22.10
+	Sp
		500281 CG23_SCHPO (31-478): 3.08e-112: 342: 35.97		YA98_SCHPO (104-564): 2.81e-90: 290: 25.20
+	Dm
		540478 CCNA_DROME (31-478): 1.48e-104: 322: 22.35		Q24044_DROME (79-576): 9.23e-88: 284: 28.76
+	Sp
		500277 CG23_SCHPO (31-478): 3.08e-112: 342: 35.97		SLP1_SCHPO (350-608): 4.19e-25: 110: 14.39
+	Hs
		538532 CCNB1_HUMAN (77-484): 1.6e-112: 341: 29.30		CDC20_HUMAN (391-604): 7.19e-25: 110: 13.45
+	Hs
		943780 CCNA1_HUMAN (63-480): 2.58e-112: 341: 22.99		CDC20_HUMAN (391-604): 7.19e-25: 110: 13.45
+	Sp
		140406 CG23_SCHPO (31-478): 3.08e-112: 342: 35.97		SRW1_SCHPO (409-609): 1.94e-18: 90.9: 15.81
+	Hs
		590171 CCNA2_HUMAN (74-479): 1.18e-104: 321: 24.65		CDC20_HUMAN (391-604): 7.19e-25: 110: 13.45
+	Hs
		538625 CCNB1_HUMAN (77-484): 1.6e-112: 341: 29.30		FZR1_HUMAN (391-606): 5.47e-17: 86.2: 13.18
+	Hs
		943810 CCNA1_HUMAN (63-480): 2.58e-112: 341: 22.99		FZR1_HUMAN (391-606): 5.47e-17: 86.2: 13.18
+	Mm
		624393 CCNB1_MOUSE (77-484): 2.72e-110: 335: 28.34		FZR1_MOUSE (391-606): 4.1e-17: 86.6: 13.18
+	Dm
		540510 CCNA_DROME (31-478): 1.48e-104: 322: 22.35		Q9W4H9_DROME (391-606): 6.01e-19: 92: 14.55
+	At
		1228250 CCB23_ARATH (69-474): 8.11e-108: 329: 23.96		FZR3_ARATH (389-601): 2.45e-16: 83.9: 13.12
+	Sp
		293340 CG23_SCHPO (31-478): 3.08e-112: 342: 35.97		MFR1_SCHPO (123-335): 1.11e-11: 68.9: 9.63
+	Hs
		590235 CCNA2_HUMAN (74-479): 1.18e-104: 321: 24.65		FZR1_HUMAN (391-606): 5.47e-17: 86.2: 13.18
+	At
		1106908 CCB12_ARATH (71-477): 1.41e-105: 323: 22.74		FZR3_ARATH (389-601): 2.45e-16: 83.9: 13.12
+	At
		1258607 CCB23_ARATH (69-474): 8.11e-108: 329: 23.96		FZR1_ARATH (391-604): 6.07e-14: 76.6: 12.96
+	At
		1106905 CCB12_ARATH (71-477): 1.41e-105: 323: 22.74		FZR2_ARATH (391-608): 9.43e-16: 82: 14.54
+	At
		1106909 CCB12_ARATH (71-477): 1.41e-105: 323: 22.74		FZR1_ARATH (391-604): 6.07e-14: 76.6: 12.96