HitPredict

Interactor 1: RPB1 (P24928)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A

Interactor 2: RPB1 (P24928)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 15282296
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_1~RNA_pol_Rpb1_1, RNA_pol_Rpb1_1~RNA_pol_Rpb1_2, RNA_pol_Rpb1_1~RNA_pol_Rpb1_3, RNA_pol_Rpb1_1~RNA_pol_Rpb1_5, RNA_pol_Rpb1_2~RNA_pol_Rpb1_2, RNA_pol_Rpb1_2~RNA_pol_Rpb1_3, RNA_pol_Rpb1_2~RNA_pol_Rpb1_4, RNA_pol_Rpb1_2~RNA_pol_Rpb1_5, RNA_pol_Rpb1_3~RNA_pol_Rpb1_4, RNA_pol_Rpb1_3~RNA_pol_Rpb1_5, RNA_pol_Rpb1_4~RNA_pol_Rpb1_5, RNA_pol_Rpb1_5~RNA_pol_Rpb1_5
Common GO terms GO:0000287 - magnesium ion binding
GO:0001055 - RNA polymerase II activity
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
and 16 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1970
Hs

1 1970
+ Hs
+ Sc
+ Sc
+ Sc
+ Sc
+ Zm
+ Hs
+ Hs
+ Hv
+ At
+ Hp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024