HitPredict

Interactor 1: RPB1 (P24928)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A

Interactor 2: RPAB4 (P53803)
DNA-directed RNA polymerases I, II, and III subunit RPABC4 (RNA polymerases I, II, and III subunit ABC4) (ABC10-alpha) (DNA-directed RNA polymerase II subunit K) (RNA polymerase II 7.0 kDa subunit) (RPB7.0) (RPB10alpha)
Gene: POLR2K

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.890

The method score is based on:

Property Details
Experiments 9201987, 35271311, 24981860, 37682711
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_RNApol_7kD~RNA_pol_Rpb1_1
Common GO terms GO:0001055 - RNA polymerase II activity
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005665 - RNA polymerase II, core complex
and 2 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1970
Hs

1 58
+ Bt
+ Sp
+ Sc
+ Hs
+ Sc
+ Sc
+ Hs
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024