Interactor 1: RPB1 (P24928)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A

Interactor 2: CDK12 (Q9NYV4)
Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) (Cell division cycle 2-related protein kinase 7) (CDC2-related protein kinase 7) (Cell division protein kinase 12) (hCDK12)
Gene: CDK12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.500

The method score is based on:

Property Details
Experiments 26659056
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006366 - transcription by RNA polymerase II
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1970
Hs

1 1490
+ Mm
+ Hs
+ At
+ At
+ At
+ Sp
+ Sc
+ Zm
+ Zm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024