Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: RBL1 (P28749)
Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1)
Gene: RBL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.762

The method score is based on:

Property Details
Experiments 8491188, 25852190, 26186194, 28514442, 9891079, 33961781, 11884610, 33422522, 35271311, 36736316, 9472014, 23602568, 23455922
Identification Methods affinity chromatography technology, enzymatic study, unspecified method, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 298
Hs

1 1068
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ At
+ Dm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024