HitPredict

Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: PRDX6 (P30041)
Peroxiredoxin-6 (EC 1.11.1.27) (1-Cys peroxiredoxin) (1-Cys PRX) (24 kDa protein) (Acidic calcium-independent phospholipase A2) (aiPLA2) (EC 3.1.1.4) (Antioxidant protein 2) (Glutathione-dependent peroxiredoxin) (Liver 2D page spot 40) (Lysophosphatidylcholine acyltransferase 5) (LPC acyltransferase 5) (LPCAT-5) (Lyso-PC acyltransferase 5) (EC 2.3.1.23) (Non-selenium glutathione peroxidase) (NSGPx) (Red blood cells page spot 12)
Gene: PRDX6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36736316, 21319273
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 224
+	Hs
		625163 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		PRDX2_HUMAN (2-204): 9.19e-90: 264: 28.99
+	Hs
		625384 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		PRDX1_HUMAN (2-204): 1.79e-87: 258: 28.37
+	Hs
		625149 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		PRDX3_HUMAN (6-204): 4.06e-86: 257: 25.12
+	Hs
		414776 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		PRDX2_HUMAN (2-204): 9.19e-90: 264: 28.99
+	Hs
		414885 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		PRDX1_HUMAN (2-204): 1.79e-87: 258: 28.37
+	Hs
		670678 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		PRDX6_HUMAN (1-224): 7.03e-104: 301: 100.00
+	Hs
		841176 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		PRDX1_HUMAN (2-204): 1.79e-87: 258: 28.37
+	Sc
		565530 PHO85_YEAST (3-290): 6.29e-131: 375: 54.88		PRX1_YEAST (4-221): 4.68e-80: 241: 47.73
+	Hs
		841185 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		PRDX4_HUMAN (3-204): 2.98e-83: 250: 24.76