HitPredict

Interactor 1: RFOX3 (A6NFN3)
RNA binding protein fox-1 homolog 3 (Fox-1 homolog C) (Neuronal nuclei antigen) (NeuN antigen)
Gene: RBFOX3

Interactor 2: RBM11 (P57052)
Splicing regulator RBM11 (RNA-binding motif protein 11)
Gene: RBM11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	35914814
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000381 - regulation of alternative mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0006397 - mRNA processing GO:0008380 - RNA splicing
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 312 Hs			1 281
+	Hs
		198845 RFOX2_HUMAN (1-312): 8.71e-44: 155: 59.38		RBMS1_HUMAN (1-267): 1.48e-36: 136: 14.44
+	Hs
		198880 RFOX2_HUMAN (1-312): 8.71e-44: 155: 59.38		ELAV2_HUMAN (2-160): 8.91e-23: 98: 16.36
+	Hs
		198894 RFOX2_HUMAN (1-312): 8.71e-44: 155: 59.38		SF3B4_HUMAN (9-111): 3.63e-21: 94: 26.67
+	Hs
		198898 RFOX2_HUMAN (1-312): 8.71e-44: 155: 59.38		ELAV1_HUMAN (2-133): 2.8e-20: 90.6: 17.24
+	Hs
		1020302 ELAV2_HUMAN (2-179): 2.77e-28: 113: 15.39		DAZL_HUMAN (3-264): 6.63e-33: 123: 19.32
+	Hs
		474019 PAB4L_HUMAN (4-175): 9.25e-37: 136: 16.76		ELAV2_HUMAN (2-160): 8.91e-23: 98: 16.36
+	Hs
		474021 PAB4L_HUMAN (4-175): 9.25e-37: 136: 16.76		PABP4_HUMAN (3-99): 7.21e-21: 94.1: 23.47
+	Hs
		668348 PABP4_HUMAN (90-186): 1.8e-20: 93.7: 19.19		RBMS1_HUMAN (1-267): 1.48e-36: 136: 14.44
+	Hs
		1031414 PABP4_HUMAN (90-186): 1.8e-20: 93.7: 19.19		DAZL_HUMAN (3-264): 6.63e-33: 123: 19.32
+	Hs
		1020259 ELAV2_HUMAN (2-179): 2.77e-28: 113: 15.39		ELAV3_HUMAN (10-91): 6.26e-24: 101: 33.74
+	Hs
		1020249 ELAV2_HUMAN (2-179): 2.77e-28: 113: 15.39		PABP4_HUMAN (3-99): 7.21e-21: 94.1: 23.47
+	Hs
		516484 ELAV2_HUMAN (2-179): 2.77e-28: 113: 15.39		PABP1_HUMAN (2-99): 9.14e-20: 90.7: 22.22
+	Hs
		1020265 ELAV2_HUMAN (2-179): 2.77e-28: 113: 15.39		ELAV1_HUMAN (2-133): 2.8e-20: 90.6: 17.24
+	Xl
		1092815 CIRBB_XENLA (100-173): 2.28e-25: 101: 36.84		ELV1A_XENLA (2-93): 3.6e-19: 87.5: 18.95
+	Hs
		516495 PABP4_HUMAN (90-186): 1.8e-20: 93.7: 19.19		PABP1_HUMAN (2-99): 9.14e-20: 90.7: 22.22
+	Hs
		1031344 PABP4_HUMAN (90-186): 1.8e-20: 93.7: 19.19		ELAV1_HUMAN (2-133): 2.8e-20: 90.6: 17.24
+	Hs
		1020353 ELAV2_HUMAN (2-179): 2.77e-28: 113: 15.39		PPIE_HUMAN (10-90): 1.92e-12: 67.8: 32.96