HitPredict

Interactor 1: RFOX3 (A6NFN3)
RNA binding protein fox-1 homolog 3 (Fox-1 homolog C) (Neuronal nuclei antigen) (NeuN antigen)
Gene: RBFOX3

Interactor 2: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26334913
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0006397 - mRNA processing GO:0008380 - RNA splicing
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 312 Hs			1 414
+	Mm
		1206622 RFOX3_MOUSE (16-312): 3.99e-48: 166: 79.13		TADBP_MOUSE (1-414): 1.47e-79: 253: 96.14
+	Hs
		62520 RFOX3_HUMAN (16-312): 4.9e-59: 193: 100.00		MSI1H_HUMAN (96-409): 4.25e-61: 203: 23.93
+	Hs
		1020246 ELAV2_HUMAN (2-179): 2.77e-28: 113: 15.39		TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00
+	Hs
		198809 RFOX2_HUMAN (1-312): 8.71e-44: 155: 59.38		MSI1H_HUMAN (96-409): 4.25e-61: 203: 23.93
+	Hs
		1025728 PABP4_HUMAN (90-186): 1.8e-20: 93.7: 19.19		TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00
+	Hs
		516491 PABP1_HUMAN (90-186): 1.01e-18: 88.3: 19.19		TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00
+	Hs
		162035 PABP4_HUMAN (90-186): 1.8e-20: 93.7: 19.19		HNRDL_HUMAN (62-376): 5.62e-71: 231: 23.60
+	Hs
		161948 PABP1_HUMAN (90-186): 1.01e-18: 88.3: 19.19		HNRDL_HUMAN (62-376): 5.62e-71: 231: 23.60
+	Hs
		516424 PABP1_HUMAN (90-186): 1.01e-18: 88.3: 19.19		ROA3_HUMAN (98-269): 2.33e-69: 225: 28.57
+	Hs
		474019 ELAV2_HUMAN (2-179): 2.77e-28: 113: 15.39		PAB4L_HUMAN (2-276): 8.18e-56: 189: 16.96
+	Hs
		474021 PAB4L_HUMAN (4-175): 9.25e-37: 136: 16.76		PABP4_HUMAN (98-274): 3.77e-37: 144: 19.02
+	Hs
		1020249 ELAV2_HUMAN (2-179): 2.77e-28: 113: 15.39		PABP4_HUMAN (98-274): 3.77e-37: 144: 19.02
+	Hs
		198951 RFOX2_HUMAN (1-312): 8.71e-44: 155: 59.38		MSI2H_HUMAN (41-207): 5.16e-20: 92.2: 23.81
+	Hs
		516484 ELAV2_HUMAN (2-179): 2.77e-28: 113: 15.39		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95
+	Mm
		665745 PABP1_MOUSE (90-186): 1.13e-18: 88.3: 19.19		TIA1_MOUSE (99-413): 1.08e-36: 139: 12.92
+	Sc
		376562 PABP_YEAST (81-186): 3.09e-19: 89.9: 16.67		PABP_YEAST (86-269): 2.74e-34: 136: 21.88
+	Hs
		516495 PABP4_HUMAN (90-186): 1.8e-20: 93.7: 19.19		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95
+	Hs
		516339 PABP1_HUMAN (90-186): 1.01e-18: 88.3: 19.19		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95
+	Sc
		376993 PABP_YEAST (81-186): 3.09e-19: 89.9: 16.67		HRP1_YEAST (101-289): 6.38e-20: 93.6: 31.50