HitPredict

Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 21319273
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 248
+	Hs
		451193 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		TPM1_HUMAN (4-248): 1.43e-48: 163: 68.16
+	Hs
		110795 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		H7BYY1_HUMAN (1-248): 8.1e-49: 162: 77.82
+	Hs
		418881 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39
+	Hs
		434344 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		TPM2_HUMAN (4-248): 5.04e-42: 146: 69.39
+	Hs
		451218 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		TPM1_HUMAN (4-248): 1.43e-48: 163: 68.16
+	Hs
		418914 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39
+	Hs
		841153 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00