Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: ORC1 (Q13415)
Origin recognition complex subunit 1 (Replication control protein 1)
Gene: ORC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.639

The method score is based on:

Property Details
Experiments 31160578, 11931757
Identification Methods affinity chromatography technology, enzymatic study, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 298
Hs

1 861
+ Hs
+ Xl
+ Dm
+ Dm
+ Hs
+ Mm
+ Hs
+ At
+ Sc
+ Sp
+ Sc
+ At

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Last updated: 15 Jul 2024