Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: CDT1 (Q9H211)
DNA replication factor Cdt1 (Double parked homolog) (DUP)
Gene: CDT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.739

The method score is based on:

Property Details
Experiments 26496610, 31160578, 15004027, 14993212, 15855168, 23455922
Identification Methods affinity chromatography technology, pull down, enzymatic study, anti tag coimmunoprecipitation, coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0045740 - positive regulation of DNA replication
GO:0051301 - cell division
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 298
Hs

1 546
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024