HitPredict

Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: LRRF2 (Q9Y608)
Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2)
Gene: LRRFIP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 721
+	Hs
		528401 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		MYH8_HUMAN (219-667): 3.37e-12: 72.6: 10.78
+	Hs
		625530 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		625177 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		MYH10_HUMAN (466-719): 8.82e-11: 67.9: 16.93
+	Hs
		625176 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		960128 CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87		MYH2_HUMAN (224-720): 4.9e-17: 88: 10.37
+	Hs
		522542 CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87		MYH1_HUMAN (218-720): 1.32e-16: 86.8: 9.27
+	Hs
		528368 CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87		MYH6_HUMAN (221-699): 6.02e-15: 81.4: 8.52
+	Hs
		522604 CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87		MYH7_HUMAN (221-688): 4.78e-14: 78.3: 8.51
+	Hs
		528405 CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87		MYH8_HUMAN (219-667): 3.37e-12: 72.6: 10.78
+	Hs
		960130 CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87		MYH15_HUMAN (269-696): 2.05e-10: 66.5: 11.74
+	Hs
		960129 CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87		MYH13_HUMAN (205-636): 4.94e-10: 65.2: 8.28
+	Hs
		502908 CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87		MYH3_HUMAN (426-721): 9.44e-10: 64.5: 16.84
+	Hs
		415005 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		DLG5_HUMAN (219-569): 1.09e-12: 74.1: 10.72
+	Hs
		725114 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		MYH10_HUMAN (466-719): 8.82e-11: 67.9: 16.93
+	Hs
		724717 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12