HitPredict

Interactor 1: PSB2 (P25043)
Proteasome subunit beta type-2 (EC 3.4.25.1) (Macropain subunit PUP1) (Multicatalytic endopeptidase complex subunit PUP1) (Proteasome component PUP1) (Proteinase YSCE subunit PUP1)
Gene: PUP1

Interactor 2: PRS7 (P33299)
26S proteasome regulatory subunit 7 homolog (Protein CIM5) (Tat-binding homolog 3)
Gene: RPT1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	37968396, 21619884
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 261 Sc			1 467
+	Sc
		675407 PSB5_YEAST (29-221): 2.42e-81: 247: 28.21		PRS7_YEAST (1-467): 2.69e-137: 405: 100.00
+	Dm
		1359417 Q9VUJ1_DROME (2-258): 8.36e-82: 248: 54.09		Q9V405_DROME (60-459): 2.26e-135: 397: 35.50
+	Hs
		730336 PSB7_HUMAN (1-258): 5.68e-84: 253: 54.75		PRS7_HUMAN (12-467): 2.4e-131: 388: 70.40
+	Sc
		625948 PSB2_YEAST (1-261): 6.21e-92: 273: 100.00		PRS10_YEAST (29-465): 2.46e-123: 367: 37.07
+	Hs
		656563 PSB6_HUMAN (22-231): 9.89e-81: 244: 28.77		PRS7_HUMAN (12-467): 2.4e-131: 388: 70.40
+	Dm
		1181055 Q9VUJ1_DROME (2-258): 8.36e-82: 248: 54.09		Q7KMQ0_DROME (12-467): 4.56e-129: 382: 68.64
+	Sp
		194879 PSA5_SCHPO (3-231): 1.73e-82: 248: 21.25		PRS7_SCHPO (1-465): 1.02e-126: 376: 73.33
+	Hs
		798737 PSB7_HUMAN (1-258): 5.68e-84: 253: 54.75		PRS6B_HUMAN (43-459): 4.68e-123: 366: 35.49
+	Dm
		1374386 Q9VUJ1_DROME (2-258): 8.36e-82: 248: 54.09		Q9W414_DROME (79-463): 7.34e-124: 367: 43.90
+	Sc
		675428 PSB5_YEAST (29-221): 2.42e-81: 247: 28.21		PRS10_YEAST (29-465): 2.46e-123: 367: 37.07
+	Hs
		907130 PSB7_HUMAN (1-258): 5.68e-84: 253: 54.75		PRS8_HUMAN (81-464): 6.1e-121: 361: 44.53
+	Dm
		186160 Q9VUJ1_DROME (2-258): 8.36e-82: 248: 54.09		PRS8_DROME (71-464): 6.18e-122: 363: 44.16
+	Hs
		913338 PSB7_HUMAN (1-258): 5.68e-84: 253: 54.75		PRS10_HUMAN (81-463): 5.38e-120: 358: 42.04
+	Hs
		656567 PSB6_HUMAN (22-231): 9.89e-81: 244: 28.77		PRS6B_HUMAN (43-459): 4.68e-123: 366: 35.49
+	Dm
		186126 Q8T8V8_DROME (29-208): 1.23e-80: 246: 28.73		PRS8_DROME (71-464): 6.18e-122: 363: 44.16
+	Hs
		656583 PSB6_HUMAN (22-231): 9.89e-81: 244: 28.77		PRS8_HUMAN (81-464): 6.1e-121: 361: 44.53
+	Sc
		625950 PSB2_YEAST (1-261): 6.21e-92: 273: 100.00		PRS8_YEAST (142-452): 2.32e-105: 320: 51.77
+	Sc
		675430 PSB5_YEAST (29-221): 2.42e-81: 247: 28.21		PRS8_YEAST (142-452): 2.32e-105: 320: 51.77
+	Zm
		32504 B4FJY5_MAIZE (2-256): 1.2e-85: 258: 53.91		A0A1D6KUI9_MAIZE (33-442): 1.22e-81: 270: 29.18
+	Hs
		656579 PSB6_HUMAN (22-231): 9.89e-81: 244: 28.77		TERA_HUMAN (33-442): 6.46e-80: 265: 28.13