HitPredict

Interactor 1: PSB2 (P25043)
Proteasome subunit beta type-2 (EC 3.4.25.1) (Macropain subunit PUP1) (Multicatalytic endopeptidase complex subunit PUP1) (Proteasome component PUP1) (Proteinase YSCE subunit PUP1)
Gene: PUP1

Interactor 2: PSB1 (P38624)
Proteasome subunit beta type-1 (EC 3.4.25.1) (Macropain subunit PRE3) (Multicatalytic endopeptidase complex subunit PRE3) (Proteasome component PRE3) (Proteinase YSCE subunit PRE3)
Gene: PRE3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.918

The method score is based on:

Property Details
Experiments 10688190, 11595789, 16554755, 9087403, 37968396
Identification Methods two hybrid, affinity chromatography technology, x-ray crystallography, two hybrid array, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pr_beta_C~Proteasome, Proteasome~Proteasome
Common GO terms GO:0000502 - proteasome complex
GO:0004175 - endopeptidase activity
GO:0004298 - threonine-type endopeptidase activity
GO:0005634 - nucleus
GO:0005829 - cytosol
and 4 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 261
Sc

1 215
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024