HitPredict

Interactor 1: PSB2 (P25043)
Proteasome subunit beta type-2 (EC 3.4.25.1) (Macropain subunit PUP1) (Multicatalytic endopeptidase complex subunit PUP1) (Proteasome component PUP1) (Proteinase YSCE subunit PUP1)
Gene: PUP1

Interactor 2: PSA4 (P40303)
Proteasome subunit alpha type-4 (Macropain subunit PRE6) (Multicatalytic endopeptidase complex subunit PRE6) (Proteasome component PRE6) (Proteinase YSCE subunit PRE6)
Gene: PRE6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 16554755, 37968396
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pr_beta_C~Proteasome, Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0004175 - endopeptidase activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 261
Sc

1 254
+ At
+ At
+ Hs
+ Sp
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Dm
+ Sc
+ Dm
+ Hs
+ Hs
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024