Interactor 1: ITIH2 (P19823)
Inter-alpha-trypsin inhibitor heavy chain H2 (ITI heavy chain H2) (ITI-HC2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP)
Gene: ITIH2

Interactor 2: ITIH1 (P19827)
Inter-alpha-trypsin inhibitor heavy chain H1 (ITI heavy chain H1) (ITI-HC1) (Inter-alpha-inhibitor heavy chain 1) (Inter-alpha-trypsin inhibitor complex component III) (Serum-derived hyaluronan-associated protein) (SHAP)
Gene: ITIH1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.90 0.586

The method score is based on:

Property Details
Experiments 37343697
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains VIT~VWA, VWA~VWA
Common GO terms GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005540 - hyaluronic acid binding
GO:0005576 - extracellular region
GO:0030212 - hyaluronan metabolic process
GO:0070062 - extracellular exosome
and 1 others

more...

Homologous interactions 0

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Last updated: 11Aug2025