HitPredict

Interactor 1: MED19 (P25046)
Mediator of RNA polymerase II transcription subunit 19 (Hypoxic gene repressor protein 3) (Mediator complex subunit 19) (Negative regulator of URS2 protein 3) (SNF1 suppressor protein 7)
Gene: ROX3

Interactor 2: MED21 (P47822)
Mediator of RNA polymerase II transcription subunit 21 (Mediator complex subunit 21) (RNAPII complex component SRB7) (Suppressor of RNA polymerase B 7)
Gene: SRB7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.55	0.679

The method score is based on:

Property	Details
Experiments	11805826, 33933450, 16554755, 37968396, 16429126
Identification Methods	tandem affinity purification, pull down, affinity chromatography technology
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003712 - transcription coregulator activity GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II and 6 others more... GO:0016592 - mediator complex GO:0032968 - positive regulation of transcription elongation by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0051123 - RNA polymerase II preinitiation complex assembly GO:0060261 - positive regulation of transcription initiation by RNA polymerase II GO:0070847 - core mediator complex
Homologous interactions	0

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Last updated: 15 Jul 2024