HitPredict

Interactor 1: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Interactor 2: ZRAN1 (Q9UGI0)
Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1)
Gene: ZRANB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18281465
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016055 - Wnt signaling pathway and 1 others more... GO:0016477 - cell migration
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2843 Hs			1 708
+	Mm
		70746 Q8BNP7_MOUSE (1-1058): 0: 1478: 95.09		OTU7B_MOUSE (322-701): 5.79e-124: 391: 25.78
+	Hs
		626224 APC_HUMAN (1-2843): 0: 1316: 100.00		RNF31_HUMAN (29-410): 7.77e-78: 271: 15.73
+	Hs
		626074 APC_HUMAN (1-2843): 0: 1316: 100.00		RBP2_HUMAN (35-380): 3.46e-21: 101: 9.86
+	Hs
		626073 APC_HUMAN (1-2843): 0: 1316: 100.00		NU153_HUMAN (109-348): 5.07e-09: 61.9: 11.11
+	Hs
		257716 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1354883 SRRM2_HUMAN (943-2827): 1.37e-30: 135: 8.96		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		654069 MAP4_HUMAN (2119-2724): 1.19e-29: 131: 15.90		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1264816 TITIN_HUMAN (717-2430): 7.06e-29: 130: 7.55		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1057011 MDC1_HUMAN (1750-2784): 3.28e-21: 104: 11.74		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		821070 PRC2A_HUMAN (951-2843): 2.17e-19: 98.6: 7.24		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		311838 TACC2_HUMAN (849-2115): 2.88e-12: 75.5: 8.26		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1186098 MICA3_HUMAN (1200-1800): 2.91e-09: 65.2: 13.62		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Dm
		1361420 Q9VAS9_DROME (215-2432): 2.92e-159: 554: 18.52		TRBID_DROME (2-140): 2.6e-16: 85: 28.48
+	Dm
		1367033 Q9Y1T2_DROME (327-1386): 2.44e-167: 550: 26.85		TRBID_DROME (2-140): 2.6e-16: 85: 28.48
+	Mm
		1208054 ANK2_MOUSE (1056-2841): 1.1e-15: 86.5: 9.74		OTU7A_MOUSE (299-701): 3.22e-123: 391: 25.33
+	Mm
		1208623 MICA3_MOUSE (1875-2670): 1.82e-12: 76: 11.40		OTU7A_MOUSE (299-701): 3.22e-123: 391: 25.33
+	Hs
		1290102 SRRM2_HUMAN (943-2827): 1.37e-30: 135: 8.96		RNF31_HUMAN (29-410): 7.77e-78: 271: 15.73
+	Hs
		834822 CIC_HUMAN (722-2643): 2.1e-17: 92.4: 7.79		RBP2_HUMAN (35-380): 3.46e-21: 101: 9.86