HitPredict

Interactor 1: WIPF3 (A6NGB9)
WAS/WASL-interacting protein family member 3 (Corticosteroids and regional expression protein 16 homolog)
Gene: WIPF3

Interactor 2: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30890647
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 483 Hs			1 377
+	Hs
		62641 WIPF3_HUMAN (33-483): 2.9e-22: 101: 100.00		ACTB_HUMAN (4-377): 0: 599: 94.12
+	Hs
		62644 WIPF3_HUMAN (33-483): 2.9e-22: 101: 100.00		ACTG_HUMAN (4-377): 0: 599: 94.39
+	Hs
		891686 MAP1A_HUMAN (3-454): 1.32e-21: 101: 13.27		ACTB_HUMAN (4-377): 0: 599: 94.12
+	Hs
		891920 WIPF2_HUMAN (31-460): 3.17e-21: 98: 27.35		ACTB_HUMAN (4-377): 0: 599: 94.12
+	Hs
		929941 WIPF2_HUMAN (31-460): 3.17e-21: 98: 27.35		ACTG_HUMAN (4-377): 0: 599: 94.39
+	Hs
		932278 WIPF2_HUMAN (31-460): 3.17e-21: 98: 27.35		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		554290 MUC1_HUMAN (83-478): 1.47e-17: 88: 12.78		ACTA_HUMAN (1-377): 0: 596: 98.41
+	Hs
		932156 MDC1_HUMAN (25-481): 1.07e-11: 69.5: 10.70		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		203220 SYNJ1_HUMAN (81-468): 1.1e-10: 66.4: 12.53		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		891853 SRCAP_HUMAN (1-467): 1.67e-09: 62.6: 13.89		ACTB_HUMAN (4-377): 0: 599: 94.12
+	Hs
		929905 SRCAP_HUMAN (1-467): 1.67e-09: 62.6: 13.89		ACTG_HUMAN (4-377): 0: 599: 94.39
+	Hs
		932219 SRCAP_HUMAN (1-467): 1.67e-09: 62.6: 13.89		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		932341 CIC_HUMAN (7-480): 6.61e-09: 60.6: 10.74		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Dm
		501445 CPN_DROME (1-437): 9.51e-09: 59.9: 10.61		ACT5_DROME (1-377): 0: 598: 93.10