HitPredict

Interactor 1: ARBK1 (P25098)
Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein coupled receptor kinase 2)
Gene: GRK2

Interactor 2: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.60	0.408

Property	Details
Experiments	17893145
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0031623 - receptor internalization and 1 others more... GO:0098794 - postsynapse
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 689 Hs			1 140
+	Hs
		742316 GRK1_HUMAN (2-530): 3.99e-148: 444: 32.60		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		742110 GRK6_HUMAN (3-543): 2.29e-139: 422: 36.25		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		681700 AKT1_HUMAN (68-515): 3.49e-140: 420: 26.41		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		714489 GRK5_HUMAN (3-567): 1.49e-136: 415: 33.86		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		1079321 GRK1_HUMAN (2-530): 3.99e-148: 444: 32.60		SYUB_HUMAN (1-126): 2.84e-36: 122: 58.02
+	Hs
		282779 GRK1_HUMAN (2-530): 3.99e-148: 444: 32.60		SYUG_HUMAN (1-100): 1.25e-28: 103: 66.00
+	Hs
		794388 GRK6_HUMAN (3-543): 2.29e-139: 422: 36.25		SYUB_HUMAN (1-126): 2.84e-36: 122: 58.02
+	Hs
		681868 AKT1_HUMAN (68-515): 3.49e-140: 420: 26.41		SYUB_HUMAN (1-126): 2.84e-36: 122: 58.02
+	Hs
		714539 GRK5_HUMAN (3-567): 1.49e-136: 415: 33.86		SYUB_HUMAN (1-126): 2.84e-36: 122: 58.02
+	Hs
		282772 GRK6_HUMAN (3-543): 2.29e-139: 422: 36.25		SYUG_HUMAN (1-100): 1.25e-28: 103: 66.00
+	Hs
		282769 GRK5_HUMAN (3-567): 1.49e-136: 415: 33.86		SYUG_HUMAN (1-100): 1.25e-28: 103: 66.00