HitPredict

Interactor 1: ADA1D (P25100)
Alpha-1D adrenergic receptor (Alpha-1A adrenergic receptor) (Alpha-1D adrenoreceptor) (Alpha-1D adrenoceptor) (Alpha-adrenergic receptor 1a)
Gene: ADRA1D

Interactor 2: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26617989
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 572 Hs			1 904
+	Hs
		656997 5HT2A_HUMAN (36-447): 3.04e-76: 251: 24.17		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Hs
		658227 5HT2C_HUMAN (116-484): 1.15e-73: 243: 26.62		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Hs
		676802 SSR1_HUMAN (73-468): 4.12e-72: 237: 22.41		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Hs
		159159 ADA1D_HUMAN (1-572): 6.03e-153: 452: 100.00		CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64
+	Hs
		626687 ADA1D_HUMAN (1-572): 6.03e-153: 452: 100.00		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		600726 DRD1_HUMAN (80-420): 7.77e-93: 293: 32.14		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Hs
		441650 ADRB1_HUMAN (25-438): 4.53e-87: 279: 29.21		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Rn
		495779 ADRB2_RAT (60-493): 4.03e-87: 277: 27.38		DLG4_RAT (86-493): 2.93e-24: 111: 15.40
+	Rn
		677498 SSR4_RAT (56-472): 8.39e-78: 252: 22.41		DLG4_RAT (86-493): 2.93e-24: 111: 15.40
+	Hs
		656994 5HT2A_HUMAN (36-447): 3.04e-76: 251: 24.17		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Mm
		830267 SSR4_MOUSE (46-472): 6.3e-77: 250: 21.43		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Mm
		676818 SSR2_MOUSE (57-449): 8.56e-77: 249: 21.18		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Hs
		658221 5HT2C_HUMAN (116-484): 1.15e-73: 243: 26.62		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Mm
		676812 SSR1_MOUSE (51-468): 8.3e-74: 242: 22.20		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Hs
		658236 5HT2C_HUMAN (116-484): 1.15e-73: 243: 26.62		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Mm
		830268 SSR4_MOUSE (46-472): 6.3e-77: 250: 21.43		DLG2_MOUSE (393-627): 3.09e-21: 101: 24.48
+	Mm
		676813 SSR1_MOUSE (51-468): 8.3e-74: 242: 22.20		DLG2_MOUSE (393-627): 3.09e-21: 101: 24.48
+	Mm
		897201 DRD2_MOUSE (321-419): 3.64e-16: 83.2: 40.40		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07