HitPredict

Interactor 1: EDNRA (P25101)
Endothelin-1 receptor (Endothelin receptor type A) (ET-A) (ETA-R) (hET-AR)
Gene: EDNRA

Interactor 2: MTX1 (Q13505)
Metaxin-1 (Mitochondrial outer membrane import complex protein 1)
Gene: MTX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007005 - mitochondrion organization
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 466
+	Hs
		208455 OX2R_HUMAN (32-422): 6.13e-70: 229: 18.87		MTX1_HUMAN (1-466): 0: 634: 100.00
+	Hs
		723297 APJ_HUMAN (71-412): 6.25e-67: 219: 22.03		MTX1_HUMAN (1-466): 0: 634: 100.00
+	Hs
		781056 OPRX_HUMAN (62-421): 1.14e-64: 213: 21.94		MTX1_HUMAN (1-466): 0: 634: 100.00
+	Hs
		198096 MTLR_HUMAN (84-377): 5.73e-16: 81.3: 22.39		MTX1_HUMAN (1-466): 0: 634: 100.00
+	Hs
		264538 EDNRA_HUMAN (1-427): 1.1e-93: 290: 100.00		MTX2_HUMAN (136-397): 9.68e-79: 247: 26.62
+	Hs
		895644 CXCR4_HUMAN (64-384): 2.46e-73: 235: 22.43		MTX3_HUMAN (150-423): 2.98e-91: 281: 50.00
+	Hs
		723315 APJ_HUMAN (71-412): 6.25e-67: 219: 22.03		MTX3_HUMAN (150-423): 2.98e-91: 281: 50.00
+	Hs
		198100 MTLR_HUMAN (84-377): 5.73e-16: 81.3: 22.39		MTX3_HUMAN (150-423): 2.98e-91: 281: 50.00