HitPredict

Interactor 1: PTAFR (P25105)
Platelet-activating factor receptor (PAF-R) (PAFr)
Gene: PTAFR

Interactor 2: ARRB1 (P49407)
Beta-arrestin-1 (Arrestin beta-1) (Non-visual arrestin-2)
Gene: ARRB1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	1.00	0.819

Property	Details
Experiments	11729201, 16709866
Identification Methods	affinity chromatography technology, fluorescent resonance energy transfer, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	7tm_1~Arrestin_C, 7tm_1~Arrestin_N
Common GO terms	GO:0005886 - plasma membrane GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 342 Hs			1 418
+	Hs
		827128 CCR5_HUMAN (12-321): 1.93e-82: 255: 24.76		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		674834 AGTR1_HUMAN (11-341): 2.5e-66: 214: 23.42		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		781016 OPRD_HUMAN (3-338): 5.09e-64: 208: 19.82		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Rn
		626613 AGTRA_RAT (11-341): 3.46e-67: 216: 24.32		ARRB1_RAT (1-418): 0: 707: 99.04
+	Mm
		669680 AGTRA_MOUSE (11-341): 1.83e-66: 215: 24.32		ARRB1_MOUSE (1-418): 0: 703: 98.57
+	Hs
		685813 APJ_HUMAN (5-337): 9.85e-73: 231: 23.44		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		428933 ADRB2_HUMAN (7-317): 1.94e-70: 227: 15.34		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Rn
		663954 Q8VBU7_RAT (7-330): 4.47e-71: 228: 14.49		ARRB2_RAT (1-407): 0: 616: 75.00
+	Hs
		626771 PTAFR_HUMAN (1-342): 1.46e-66: 214: 100.00		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		674827 AGTR1_HUMAN (11-341): 2.5e-66: 214: 23.42		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		685822 OPRD_HUMAN (3-338): 5.09e-64: 208: 19.82		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Rn
		626614 AGTRA_RAT (11-341): 3.46e-67: 216: 24.32		ARRB2_RAT (1-407): 0: 616: 75.00