Interactor 1: ACKR3 (P25106)
Atypical chemokine receptor 3 (C-X-C chemokine receptor type 7) (CXC-R7) (CXCR-7) (Chemokine orphan receptor 1) (G-protein coupled receptor 159) (G-protein coupled receptor RDC1 homolog) (RDC-1)
Gene: ACKR3

Interactor 2: ADA1A (P35348)
Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c)
Gene: ADRA1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 28862946
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~7tm_1
Common GO terms GO:0005886 - plasma membrane
GO:0007204 - positive regulation of cytosolic calcium ion concentration
GO:0008285 - negative regulation of cell population proliferation
GO:0043231 - intracellular membrane-bounded organelle
GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024