Interactor 1: TNR1A (P25118)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a)
Gene: Tnfrsf1a

Interactor 2: IRAK1 (Q62406)
Interleukin-1 receptor-associated kinase 1 (IRAK) (IRAK-1) (EC 2.7.11.1) (Pelle-like protein kinase) (mPLK)
Gene: IRAK1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 18562480
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Death~Death
Common GO terms GO:0005886 - plasma membrane
GO:0019221 - cytokine-mediated signaling pathway
GO:0032991 - protein-containing complex
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 454
Mm

1 710
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024