Interactor 1: CAN8 (A6NHC0)
Calpain-8 (EC 3.4.22.53) (New calpain 2) (nCL-2) (Stomach-specific M-type calpain)
Gene: CAPN8

Interactor 2: ICAL (P20810)
Calpastatin (Calpain inhibitor) (Sperm BS-17 component)
Gene: CAST

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Calpain_III~Calpain_inhib, Calpain_inhib~Peptidase_C2
Common GO terms GO:0005737 - cytoplasm
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 703
Hs

1 708
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024