HitPredict

Interactor 1: SUZ2 (P25172)
Protein suppressor 2 of zeste (Protein posterior sex combs)
Gene: Su(z)2

Interactor 2: SMBT (Q9VK33)
Polycomb protein Sfmbt (Scm-like with four MBT domain-containing protein 1) (dSfmbt)
Gene: Sfmbt

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	36070387
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0008270 - zinc ion binding GO:0031507 - heterochromatin formation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1368 Dm			1 1220
+	Dm
		728810 PSC_DROME (19-535): 2.1e-97: 346: 24.12		SMBT_DROME (1-1220): 0: 1735: 100.00
+	Dm
		627164 SUZ2_DROME (1-1368): 0: 1412: 100.00		PHP_DROME (978-1210): 1.41e-45: 182: 19.58
+	Dm
		627168 SUZ2_DROME (1-1368): 0: 1412: 100.00		Q9NF31_DROME (978-1210): 2.08e-42: 171: 19.50
+	Dm
		627170 SUZ2_DROME (1-1368): 0: 1412: 100.00		SCM_DROME (273-647): 3.33e-14: 79.9: 16.10
+	Mm
		886508 PCGF6_MOUSE (10-237): 1.34e-78: 265: 22.98		LMBL2_MOUSE (535-1055): 0: 625: 43.86
+	Hs
		1282142 PCGF6_HUMAN (10-237): 3.92e-77: 261: 22.18		LMBL2_HUMAN (535-1058): 0: 623: 43.53
+	Dm
		728795 PSC_DROME (19-535): 2.1e-97: 346: 24.12		PHP_DROME (978-1210): 1.41e-45: 182: 19.58
+	Dm
		728804 PSC_DROME (19-535): 2.1e-97: 346: 24.12		Q9NF31_DROME (978-1210): 2.08e-42: 171: 19.50
+	Mm
		620786 PCGF2_MOUSE (25-334): 3.3e-82: 275: 24.85		PHC1_MOUSE (955-1202): 4.94e-53: 204: 20.76
+	Hs
		943088 PCGF6_HUMAN (10-237): 3.92e-77: 261: 22.18		PHC1_HUMAN (955-1202): 7.33e-51: 197: 20.38
+	Hs
		717684 BMI1_HUMAN (25-338): 1.31e-76: 259: 28.74		PHC1_HUMAN (955-1202): 7.33e-51: 197: 20.38
+	Mm
		620794 PCGF2_MOUSE (25-334): 3.3e-82: 275: 24.85		PHC2_MOUSE (970-1201): 2.24e-43: 173: 17.62
+	Dm
		764516 Q9VV77_DROME (25-228): 8.28e-81: 266: 25.11		PHP_DROME (978-1210): 1.41e-45: 182: 19.58
+	Hs
		1220909 R4GMX3_HUMAN (21-338): 8.23e-78: 267: 28.41		PHC2_HUMAN (970-1201): 1.74e-43: 173: 17.62
+	Dm
		1341979 Q9VV77_DROME (25-228): 8.28e-81: 266: 25.11		Q9NF31_DROME (978-1210): 2.08e-42: 171: 19.50
+	Dm
		1374688 Q9VV77_DROME (25-228): 8.28e-81: 266: 25.11		Q9W523_DROME (978-1210): 8.59e-42: 170: 19.50
+	Hs
		1220886 PCGF6_HUMAN (10-237): 3.92e-77: 261: 22.18		PHC2_HUMAN (970-1201): 1.74e-43: 173: 17.62
+	Dm
		728808 PSC_DROME (19-535): 2.1e-97: 346: 24.12		SCM_DROME (273-647): 3.33e-14: 79.9: 16.10
+	Mm
		620790 PCGF2_MOUSE (25-334): 3.3e-82: 275: 24.85		PHC3_MOUSE (994-1201): 1.88e-32: 139: 19.07
+	Hs
		1242734 PCGF6_HUMAN (10-237): 3.92e-77: 261: 22.18		PHC3_HUMAN (994-1202): 3.35e-32: 138: 18.98