HitPredict

Interactor 1: MCM3 (P25205)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102)
Gene: MCM3

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	26527279, 29760279, 26167883
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 808 Hs			1 136
+	Hs
		832357 MCM2_HUMAN (10-721): 0: 707: 30.62		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		832495 MCM2_HUMAN (10-721): 0: 707: 30.62		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Mm
		935446 MCM2_MOUSE (10-721): 0: 706: 30.07		H31_MOUSE (1-136): 2.8e-62: 188: 100.00
+	Hs
		832369 MCM2_HUMAN (10-721): 0: 707: 30.62		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		832541 MCM2_HUMAN (10-721): 0: 707: 30.62		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Mm
		952736 MCM2_MOUSE (10-721): 0: 706: 30.07		H33_MOUSE (1-136): 2.73e-61: 186: 96.32
+	Mm
		952250 MCM2_MOUSE (10-721): 0: 706: 30.07		H32_MOUSE (1-136): 6.5e-61: 185: 99.27
+	Mm
		935447 MCM6_MOUSE (2-800): 0: 693: 26.53		H31_MOUSE (1-136): 2.8e-62: 188: 100.00
+	Mm
		952737 MCM6_MOUSE (2-800): 0: 693: 26.53		H33_MOUSE (1-136): 2.73e-61: 186: 96.32
+	Mm
		952251 MCM6_MOUSE (2-800): 0: 693: 26.53		H32_MOUSE (1-136): 6.5e-61: 185: 99.27
+	Hs
		934761 MCM6_HUMAN (2-800): 0: 688: 26.50		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		952336 MCM6_HUMAN (2-800): 0: 688: 26.50		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		708603 MCM5_HUMAN (9-713): 0: 685: 28.92		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		708661 MCM5_HUMAN (9-713): 0: 685: 28.92		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		708605 MCM5_HUMAN (9-713): 0: 685: 28.92		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		708690 MCM5_HUMAN (9-713): 0: 685: 28.92		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		708677 MCM5_HUMAN (9-713): 0: 685: 28.92		H37_HUMAN (1-136): 5.62e-59: 180: 97.06
+	Hs
		708683 MCM5_HUMAN (9-713): 0: 685: 28.92		H3C_HUMAN (1-136): 5.49e-58: 177: 93.38
+	Hs
		828172 MCM2_HUMAN (10-721): 0: 707: 30.62		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Sc
		667566 MCM2_YEAST (6-668): 0: 664: 32.15		CENPA_YEAST (18-134): 2.12e-41: 138: 55.83