HitPredict

Interactor 1: MCM3 (P25205)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102)
Gene: MCM3

Interactor 2: MCMBP (Q9BTE3)
Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein)
Gene: MCMBP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.758

Property	Details
Experiments	28514442, 27621311, 17296731, 30108253, 33961781, 22540012, 24190967, 25036637, 24299456
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 808 Hs			1 642
+	Mm
		627414 MCM3_MOUSE (1-808): 0: 922: 92.64		MCMBP_MOUSE (1-642): 0: 998: 92.99
+	Hs
		832682 MCM2_HUMAN (10-721): 0: 707: 30.62		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	Hs
		1055618 MCM6_HUMAN (2-800): 0: 688: 26.50		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	Hs
		708753 MCM5_HUMAN (9-713): 0: 685: 28.92		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	Hs
		708504 MCM4_HUMAN (9-739): 0: 661: 28.03		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	Hs
		709032 MCM7_HUMAN (10-669): 0: 650: 31.62		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	Dm
		1370623 MCM3_DROME (12-808): 0: 856: 61.35		MCMBP_DROME (1-632): 0: 724: 35.47
+	At
		1119353 MCM3_ARATH (6-808): 0: 823: 48.27		MCMBP_ARATH (4-632): 0: 685: 31.38
+	Dm
		1366520 MCM5_DROME (2-722): 0: 677: 28.59		MCMBP_DROME (1-632): 0: 724: 35.47
+	At
		1119356 MCM2_ARATH (1-668): 0: 686: 30.09		MCMBP_ARATH (4-632): 0: 685: 31.38
+	At
		99162 MCM6_ARATH (9-778): 0: 665: 27.60		MCMBP_ARATH (4-632): 0: 685: 31.38
+	At
		1013294 MCM4_ARATH (14-684): 0: 664: 31.03		MCMBP_ARATH (4-632): 0: 685: 31.38
+	At
		795006 MCM7_ARATH (13-721): 0: 662: 30.20		MCMBP_ARATH (4-632): 0: 685: 31.38
+	Sp
		293432 MCM3_SCHPO (4-808): 0: 747: 44.61		YFF4_SCHPO (341-623): 6.68e-102: 321: 25.09
+	Sp
		293433 MCM2_SCHPO (1-668): 0: 674: 32.31		YFF4_SCHPO (341-623): 6.68e-102: 321: 25.09
+	At
		285822 MCM5_ARATH (37-648): 4.5e-91: 303: 34.76		MCMBP_ARATH (4-632): 0: 685: 31.38
+	Sp
		293434 MCM5_SCHPO (1-661): 0: 653: 31.23		YFF4_SCHPO (341-623): 6.68e-102: 321: 25.09
+	Sp
		293431 MCM4_SCHPO (109-652): 1.84e-87: 298: 34.15		YFF4_SCHPO (341-623): 6.68e-102: 321: 25.09
+	Sp
		252654 MCM7_SCHPO (109-649): 5.71e-86: 291: 36.55		YFF4_SCHPO (341-623): 6.68e-102: 321: 25.09