HitPredict

Interactor 1: SIS1 (P25294)
Protein SIS1
Gene: SIS1

Interactor 2: TAH1 (P25638)
TPR repeat-containing protein associated with Hsp90
Gene: TAH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006457 - protein folding GO:0051087 - protein-folding chaperone binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 352 Sc			1 111
+	Hs
		1262156 DNJA4_HUMAN (1-352): 3.62e-119: 351: 28.65		SGTB_HUMAN (1-111): 2.22e-37: 129: 32.14
+	Hs
		681648 DNJA1_HUMAN (1-352): 2.53e-121: 357: 28.93		CHIP_HUMAN (2-104): 1.17e-31: 114: 27.89
+	Hs
		243670 DNJA2_HUMAN (2-352): 5.07e-121: 356: 28.09		CHIP_HUMAN (2-104): 1.17e-31: 114: 27.89
+	Hs
		1262171 DNJA4_HUMAN (1-352): 3.62e-119: 351: 28.65		CHIP_HUMAN (2-104): 1.17e-31: 114: 27.89
+	Hs
		279360 DNJB5_HUMAN (5-352): 6.21e-116: 341: 33.52		CHIP_HUMAN (2-104): 1.17e-31: 114: 27.89
+	Hs
		858603 DJB13_HUMAN (6-352): 1.55e-109: 323: 27.97		PPP5_HUMAN (1-107): 1.08e-32: 120: 20.37
+	Hs
		636443 DNJB1_HUMAN (5-352): 5.62e-109: 323: 34.09		CHIP_HUMAN (2-104): 1.17e-31: 114: 27.89
+	Hs
		681339 DNJA1_HUMAN (1-352): 2.53e-121: 357: 28.93		STIP1_HUMAN (4-110): 5.68e-09: 54: 17.16
+	Hs
		243309 DNJA2_HUMAN (2-352): 5.07e-121: 356: 28.09		STIP1_HUMAN (4-110): 5.68e-09: 54: 17.16
+	Hs
		279279 DNJB5_HUMAN (5-352): 6.21e-116: 341: 33.52		STIP1_HUMAN (4-110): 5.68e-09: 54: 17.16
+	Sc
		633677 MAS5_YEAST (1-352): 1.41e-111: 332: 28.13		SGT2_YEAST (2-89): 1.2e-10: 58.5: 27.27
+	Dm
		247620 Q9VFV9_DROME (1-352): 8.97e-112: 332: 28.25		O61650_DROME (5-79): 1.81e-09: 55.1: 33.33
+	Hs
		685080 DNJB4_HUMAN (5-352): 1.08e-112: 332: 34.08		STIP1_HUMAN (4-110): 5.68e-09: 54: 17.16
+	Hs
		636254 DNJB1_HUMAN (5-352): 5.62e-109: 323: 34.09		STIP1_HUMAN (4-110): 5.68e-09: 54: 17.16
+	Sc
		628575 SIS1_YEAST (1-352): 6.96e-105: 313: 100.00		SGT2_YEAST (2-89): 1.2e-10: 58.5: 27.27