HitPredict

Interactor 1: SIS1 (P25294)
Protein SIS1
Gene: SIS1

Interactor 2: EF2 (P32324)
Elongation factor 2 (EF-2) (EC 3.6.5.-) (Eukaryotic elongation factor 2) (eEF2) (Ribosomal translocase) (Translation elongation factor 2)
Gene: EFT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	33326013, 37845327, 19536198
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0051087 - protein-folding chaperone binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 352 Sc			1 842
+	Sc
		633023 MAS5_YEAST (1-352): 1.41e-111: 332: 28.13		EF2_YEAST (1-842): 0: 957: 100.00
+	Hs
		681455 DNJA1_HUMAN (1-352): 2.53e-121: 357: 28.93		U5S1_HUMAN (1-840): 0: 813: 36.35
+	Hs
		243412 DNJA2_HUMAN (2-352): 5.07e-121: 356: 28.09		U5S1_HUMAN (1-840): 0: 813: 36.35
+	Hs
		1064525 DNJA4_HUMAN (1-352): 3.62e-119: 351: 28.65		U5S1_HUMAN (1-840): 0: 813: 36.35
+	Hs
		1064804 DNJB4_HUMAN (5-352): 1.08e-112: 332: 34.08		U5S1_HUMAN (1-840): 0: 813: 36.35
+	Hs
		636335 DNJB1_HUMAN (5-352): 5.62e-109: 323: 34.09		U5S1_HUMAN (1-840): 0: 813: 36.35
+	Sc
		633129 MAS5_YEAST (1-352): 1.41e-111: 332: 28.13		SN114_YEAST (2-839): 0: 580: 25.06
+	Sc
		627917 SIS1_YEAST (1-352): 6.96e-105: 313: 100.00		SN114_YEAST (2-839): 0: 580: 25.06
+	Ec
		442650 DNAJ_ECOLI (2-351): 3.01e-107: 320: 26.48		EFG_ECOLI (14-816): 0: 572: 21.95
+	Sc
		625873 SIS1_YEAST (1-352): 6.96e-105: 313: 100.00		EFGM_YEAST (6-829): 0: 562: 19.43