HitPredict

Interactor 1: SIS1 (P25294)
Protein SIS1
Gene: SIS1

Interactor 2: ARPC1 (P38328)
Actin-related protein 2/3 complex subunit 1 (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene: ARC40

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 352 Sc			1 384
+	Hs
		681549 DNJA1_HUMAN (1-352): 2.53e-121: 357: 28.93		FBXW7_HUMAN (1-321): 3.45e-66: 224: 11.89
+	Hs
		243532 DNJA2_HUMAN (2-352): 5.07e-121: 356: 28.09		FBXW7_HUMAN (1-321): 3.45e-66: 224: 11.89
+	Sc
		633184 MAS5_YEAST (1-352): 1.41e-111: 332: 28.13		ARPC1_YEAST (1-384): 7.16e-76: 241: 96.62
+	Hs
		243501 DNJA2_HUMAN (2-352): 5.07e-121: 356: 28.09		POC1A_HUMAN (144-384): 3.45e-45: 162: 11.93
+	Hs
		243354 DNJA2_HUMAN (2-352): 5.07e-121: 356: 28.09		WDR5_HUMAN (182-383): 7.51e-36: 135: 12.75
+	Sc
		633441 MAS5_YEAST (1-352): 1.41e-111: 332: 28.13		COPA_YEAST (2-371): 4.32e-26: 112: 8.66
+	Sc
		628316 SIS1_YEAST (1-352): 6.96e-105: 313: 100.00		COPA_YEAST (2-371): 4.32e-26: 112: 8.66
+	Hs
		1309166 DNJB4_HUMAN (5-352): 1.08e-112: 332: 34.08		TBL1Y_HUMAN (52-384): 8.43e-20: 92.7: 12.77
+	Hs
		245646 DNJB4_HUMAN (5-352): 1.08e-112: 332: 34.08		TBL1X_HUMAN (55-297): 3.08e-19: 91.1: 13.67
+	Hs
		636407 DNJB1_HUMAN (5-352): 5.62e-109: 323: 34.09		TBL1Y_HUMAN (52-384): 8.43e-20: 92.7: 12.77
+	Hs
		245562 DNJB1_HUMAN (5-352): 5.62e-109: 323: 34.09		TBL1X_HUMAN (55-297): 3.08e-19: 91.1: 13.67
+	Zm
		21712 A0A1D6PWA4_MAIZE (4-351): 6.91e-113: 338: 24.86		A0A1D6HWP6_MAIZE (91-304): 2.66e-13: 72.3: 12.89
+	Sc
		628446 SIS1_YEAST (1-352): 6.96e-105: 313: 100.00		SEC13_YEAST (19-190): 1.7e-09: 60.3: 13.33