HitPredict

Interactor 1: SIS1 (P25294)
Protein SIS1
Gene: SIS1

Interactor 2: NDC80 (P40460)
Kinetochore protein NDC80 (80 kDa spindle component protein) (Nuclear division cycle protein 80) (Two-hybrid interaction with DMC1 protein 3)
Gene: NDC80

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31919192, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 352 Sc			1 691
+	Hs
		279327 DNJB5_HUMAN (5-352): 6.21e-116: 341: 33.52		DLG5_HUMAN (281-690): 1.87e-21: 102: 9.71
+	Hs
		243421 DNJA2_HUMAN (2-352): 5.07e-121: 356: 28.09		ITSN1_HUMAN (440-691): 1.27e-09: 64: 8.68
+	Hs
		148439 DNJA1_HUMAN (1-352): 2.53e-121: 357: 28.93		CTRO_HUMAN (301-647): 2.93e-09: 62.6: 15.16
+	Sc
		630951 MAS5_YEAST (1-352): 1.41e-111: 332: 28.13		USO1_YEAST (258-682): 1.9e-10: 66.5: 14.71
+	Sc
		627730 SIS1_YEAST (1-352): 6.96e-105: 313: 100.00		USO1_YEAST (258-682): 1.9e-10: 66.5: 14.71