Interactor 1: ISK2 (P20155)
Serine protease inhibitor Kazal-type 2 (Acrosin-trypsin inhibitor) (Epididymis tissue protein Li 172) (HUSI-II)
Gene: SPINK2
Interactor 2: KLK4 (Q9Y5K2)
Kallikrein-4 (EC 3.4.21.-) (Enamel matrix serine proteinase 1) (Kallikrein-like protein 1) (KLK-L1) (Prostase) (Serine protease 17)
Gene: KLK4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 0.90 | 0.657 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31391482 |
| Identification Methods | surface plasmon resonance, x-ray crystallography |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Kazal_1~Trypsin |
| Common GO terms | GO:0005576 - extracellular region |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
