HitPredict

Interactor 1: MSH3 (P25336)
DNA mismatch repair protein MSH3 (Mismatch-binding protein) (MBP) (MutS protein homolog 3)
Gene: MSH3

Interactor 2: MLH1 (P38920)
DNA mismatch repair protein MLH1 (MutL protein homolog 1) (Post meiotic segregation protein 2)
Gene: MLH1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 24550389, 24811092
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HATPase_c_3~MutS_II, HATPase_c_3~MutS_III, HATPase_c_3~MutS_V
Common GO terms GO:0000710 - meiotic mismatch repair
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006298 - mismatch repair
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1018
Sc

1 769
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Ec
+ Sc
+ Sc
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024