Interactor 1: ERG4 (P25340)
Delta(24(24(1)))-sterol reductase ERG4 (EC 1.3.1.71) (C-24(28) sterol reductase ERG4) (Ergosterol biosynthetic protein 4) (Sterol Delta(24(28))-reductase ERG4)
Gene: ERG4

Interactor 2: ERG24 (P32462)
Delta(14)-sterol reductase ERG24 (EC 1.3.1.70) (C-14 sterol reductase ERG24) (Ergosterol biosynthetic protein 24) (Sterol C14-reductase ERG24)
Gene: ERG24

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 37968396, 16300994
Identification Methods affinity chromatography technology, protein complementation assay, ubiquitin reconstruction
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ERG4_ERG24~ERG4_ERG24
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0006696 - ergosterol biosynthetic process
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 473
Sc

1 438
+ Sc
+ Sc
+ Zm

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Last updated: 15 Jul 2024