HitPredict

Interactor 1: OCA4 (P25366)
Protein OCA4 (Oxidant-induced cell-cycle arrest protein 4)
Gene: OCA4

Interactor 2: OCA1 (P50946)
Putative tyrosine-protein phosphatase OCA1 (EC 3.1.3.48) (Oxidant-induced cell-cycle arrest protein 1)
Gene: OCA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.864

Property	Details
Experiments	11283351, 16429126, 37968396
Identification Methods	two hybrid pooling approach, affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Y_phosphatase2~Y_phosphatase2
Common GO terms	GO:0005737 - cytoplasm GO:0016791 - phosphatase activity
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 362 Sc			1 238
+	Sc
		630381 OCA4_YEAST (1-362): 0: 538: 100.00		SIW14_YEAST (20-223): 1.43e-80: 244: 32.04
+	Sc
		630385 OCA4_YEAST (1-362): 0: 538: 100.00		OCA6_YEAST (67-230): 6.65e-59: 187: 24.16
+	Sc
		630380 OCA4_YEAST (1-362): 0: 538: 100.00		OCA2_YEAST (65-232): 7.48e-59: 186: 34.48
+	At
		1195865 DSP2_ARATH (2-207): 4.3e-68: 216: 23.22		DSP2_ARATH (17-223): 3.18e-90: 268: 24.19
+	Sc
		842770 SIW14_YEAST (2-227): 5.06e-43: 152: 20.00		OCA1_YEAST (1-238): 1.27e-110: 319: 100.00
+	Sc
		842773 OCA6_YEAST (2-209): 2.17e-42: 148: 19.54		OCA1_YEAST (1-238): 1.27e-110: 319: 100.00
+	Sc
		842769 OCA2_YEAST (3-205): 2.3e-39: 140: 18.75		OCA1_YEAST (1-238): 1.27e-110: 319: 100.00
+	Sc
		866755 SIW14_YEAST (2-227): 5.06e-43: 152: 20.00		OCA6_YEAST (67-230): 6.65e-59: 187: 24.16
+	Sc
		866674 SIW14_YEAST (2-227): 5.06e-43: 152: 20.00		OCA2_YEAST (65-232): 7.48e-59: 186: 34.48
+	Sc
		866676 OCA6_YEAST (2-209): 2.17e-42: 148: 19.54		OCA2_YEAST (65-232): 7.48e-59: 186: 34.48