HitPredict

Interactor 1: NCF1B (A6NI72)
Putative neutrophil cytosol factor 1B (NCF-1B) (Putative SH3 and PX domain-containing protein 1B)
Gene: NCF1B

Interactor 2: SH3G3 (Q99963)
Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)
Gene: SH3GL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	NECFESHC~SH3_1, SH3_1~p47_phox_C, SH3_1~SH3_1
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 391 Hs			1 347
+	Hs
		537667 NCF1_HUMAN (1-391): 1.31e-100: 305: 98.98		SH3G3_HUMAN (1-347): 9.83e-90: 274: 100.00
+	Hs
		537666 NCF1_HUMAN (1-391): 1.31e-100: 305: 98.98		SH3G1_HUMAN (1-347): 7.8e-80: 249: 66.30
+	Hs
		537645 NCF1_HUMAN (1-391): 1.31e-100: 305: 98.98		SRC8_HUMAN (7-343): 2.64e-50: 177: 14.49
+	Hs
		537657 NCF1_HUMAN (1-391): 1.31e-100: 305: 98.98		SH3R1_HUMAN (271-339): 2.43e-11: 66.8: 20.83
+	Hs
		537619 NCF1_HUMAN (1-391): 1.31e-100: 305: 98.98		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Rn
		192737 SRBS2_RAT (34-284): 8.37e-14: 75.1: 16.08		SH3G1_RAT (1-347): 1.14e-78: 246: 66.30
+	Hs
		1052195 SRC8_HUMAN (25-283): 5.24e-35: 137: 12.03		SRC8_HUMAN (7-343): 2.64e-50: 177: 14.49
+	Rn
		71363 B2RZ33_RAT (161-384): 6.2e-22: 98.2: 14.56		SRC8_RAT (7-343): 1.63e-50: 177: 13.53
+	Hs
		1052226 SRC8_HUMAN (25-283): 5.24e-35: 137: 12.03		RHG17_HUMAN (6-251): 2.42e-35: 138: 20.83
+	Hs
		1126373 SH319_HUMAN (123-282): 1.91e-27: 116: 17.50		SH3Y1_HUMAN (139-341): 5.08e-38: 140: 19.73
+	Hs
		1148372 DNMBP_HUMAN (162-282): 1.18e-11: 68.7: 19.23		RHG17_HUMAN (6-251): 2.42e-35: 138: 20.83
+	Hs
		924570 SRC8_HUMAN (25-283): 5.24e-35: 137: 12.03		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Mm
		139640 SH319_MOUSE (114-304): 3.59e-13: 72.9: 18.57		SH3Y1_MOUSE (132-341): 2.19e-33: 128: 18.42
+	Hs
		1126368 SH319_HUMAN (123-282): 1.91e-27: 116: 17.50		SH3R1_HUMAN (271-339): 2.43e-11: 66.8: 20.83
+	Hs
		924617 SH319_HUMAN (123-282): 1.91e-27: 116: 17.50		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		209154 NCK2_HUMAN (162-373): 2.41e-20: 93.6: 13.28		SRBS1_HUMAN (169-342): 1.13e-13: 74.1: 17.65
+	Hs
		557655 NCK1_HUMAN (161-384): 3.94e-22: 98.6: 13.79		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		208967 NCK2_HUMAN (162-373): 2.41e-20: 93.6: 13.28		SRBS2_HUMAN (291-344): 2.01e-10: 64.3: 48.15
+	Hs
		298986 SRBS2_HUMAN (164-284): 6.05e-18: 88.1: 21.15		SH3R1_HUMAN (271-339): 2.43e-11: 66.8: 20.83
+	Hs
		298942 SRBS2_HUMAN (164-284): 6.05e-18: 88.1: 21.15		SRBS2_HUMAN (291-344): 2.01e-10: 64.3: 48.15