HitPredict

Interactor 1: SSK22 (P25390)
Serine/threonine-protein kinase SSK22 (EC 2.7.11.1) (MAP kinase kinase kinase SSK22) (Suppressor of sensor kinase 22)
Gene: SSK22

Interactor 2: APJ1 (P53940)
J domain-containing protein APJ1
Gene: APJ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	DnaJ~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1331 Sc			1 528
+	Sc
		633440 SSK2_YEAST (4-1315): 0: 1374: 49.89		MAS5_YEAST (1-461): 1.1e-113: 344: 31.93
+	Hs
		681410 KPCE_HUMAN (918-1330): 1.27e-117: 386: 19.39		DNJA1_HUMAN (1-484): 1.22e-126: 377: 26.88
+	Hs
		636451 MAST1_HUMAN (796-1331): 3.22e-123: 421: 19.49		DNJB1_HUMAN (5-427): 1.1e-95: 295: 21.93
+	At
		187511 CIPKB_ARATH (1032-1319): 3.41e-120: 382: 28.13		DNAJ3_ARATH (2-487): 2.9e-103: 318: 24.34
+	Sc
		866408 BCK1_YEAST (1034-1309): 2.35e-42: 172: 35.69		APJ1_YEAST (1-528): 0: 522: 100.00
+	Hs
		636252 AKT1_HUMAN (905-1331): 1.81e-119: 382: 20.44		DNJB1_HUMAN (5-427): 1.1e-95: 295: 21.93
+	Hs
		681575 M3K3_HUMAN (1032-1305): 1.89e-38: 155: 35.74		DNJA1_HUMAN (1-484): 1.22e-126: 377: 26.88
+	Sc
		633490 BCK1_YEAST (1034-1309): 2.35e-42: 172: 35.69		MAS5_YEAST (1-461): 1.1e-113: 344: 31.93
+	Sc
		618312 STE11_YEAST (1034-1310): 8.33e-41: 164: 31.13		MAS5_YEAST (1-461): 1.1e-113: 344: 31.93
+	Hs
		1290477 M3K3_HUMAN (1032-1305): 1.89e-38: 155: 35.74		DNJA3_HUMAN (5-467): 1.5e-111: 341: 21.14
+	Hs
		1306391 M3K3_HUMAN (1032-1305): 1.89e-38: 155: 35.74		DNJB4_HUMAN (5-428): 2.53e-97: 300: 21.46
+	Hs
		636404 M3K3_HUMAN (1032-1305): 1.89e-38: 155: 35.74		DNJB1_HUMAN (5-427): 1.1e-95: 295: 21.93