HitPredict

Interactor 1: BRD2 (P25440)
Bromodomain-containing protein 2 (O27.1.1)
Gene: BRD2

Interactor 2: TAF6 (P49848)
Transcription initiation factor TFIID subunit 6 (RNA polymerase II TBP-associated factor subunit E) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) (Transcription initiation factor TFIID 80 kDa subunit) (TAF(II)80) (TAFII-80) (TAFII80)
Gene: TAF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31753913, 30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 801 Hs			1 677
+	Hs
		836225 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		TAF6_HUMAN (1-677): 0: 860: 100.00
+	Hs
		836238 BRDT_HUMAN (48-763): 4.45e-106: 349: 45.39		TAF6_HUMAN (1-677): 0: 860: 100.00
+	Hs
		244122 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		TAF6_HUMAN (1-677): 0: 860: 100.00
+	Hs
		836213 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		TAF6_HUMAN (1-677): 0: 860: 100.00
+	Hs
		836260 KAT2A_HUMAN (293-452): 5.67e-30: 129: 24.38		TAF6_HUMAN (1-677): 0: 860: 100.00
+	Hs
		600101 TAF1_HUMAN (64-263): 1.16e-16: 87.2: 16.00		TAF6_HUMAN (1-677): 0: 860: 100.00
+	Hs
		836257 PHIP_HUMAN (76-730): 1.12e-13: 77.6: 11.21		TAF6_HUMAN (1-677): 0: 860: 100.00
+	Hs
		245145 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		TAF6L_HUMAN (5-564): 1.8e-144: 436: 19.67
+	Sc
		858562 GCN5_YEAST (275-456): 2.99e-40: 155: 26.63		TAF6_YEAST (7-446): 1.55e-161: 476: 28.96
+	Sp
		251532 YK82_SCHPO (27-186): 5.63e-31: 132: 29.88		TAF6_SCHPO (9-415): 7.2e-163: 477: 37.32
+	Mm
		1246827 KAT2A_MOUSE (293-452): 2.79e-29: 127: 24.38		TAF6L_MOUSE (5-564): 3.03e-155: 464: 20.20
+	Sc
		728723 BDF1_YEAST (16-240): 5.3e-20: 97.2: 22.47		TAF6_YEAST (7-446): 1.55e-161: 476: 28.96
+	Hs
		1271524 KAT2B_HUMAN (293-452): 1.59e-31: 134: 25.00		TAF6L_HUMAN (5-564): 1.8e-144: 436: 19.67
+	Hs
		1271478 KAT2A_HUMAN (293-452): 5.67e-30: 129: 24.38		TAF6L_HUMAN (5-564): 1.8e-144: 436: 19.67