HitPredict

Interactor 1: BRD2 (P25440)
Bromodomain-containing protein 2 (O27.1.1)
Gene: BRD2

Interactor 2: NOLC1 (Q14978)
Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130)
Gene: NOLC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30554943, 36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 801 Hs			1 699
+	Hs
		631406 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		TOP2B_HUMAN (6-463): 1.53e-66: 241: 14.13
+	Hs
		508826 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44
+	Hs
		973337 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		TOP2B_HUMAN (6-463): 1.53e-66: 241: 14.13
+	Hs
		1060988 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		NOLC1_HUMAN (1-699): 6.47e-68: 237: 100.00
+	Hs
		631500 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		SRRM1_HUMAN (8-680): 2.28e-09: 62.7: 9.64
+	Hs
		244311 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		TOP2B_HUMAN (6-463): 1.53e-66: 241: 14.13
+	Hs
		244451 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		NOLC1_HUMAN (1-699): 6.47e-68: 237: 100.00
+	Hs
		509005 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44
+	Hs
		243848 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44
+	Hs
		1067006 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		NIPBL_HUMAN (62-535): 1.22e-09: 63.9: 13.77
+	Hs
		1067043 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		SRRM1_HUMAN (8-680): 2.28e-09: 62.7: 9.64
+	Hs
		1123378 BRDT_HUMAN (48-763): 4.45e-106: 349: 45.39		SRRM1_HUMAN (8-680): 2.28e-09: 62.7: 9.64
+	Hs
		973319 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		TOP2B_HUMAN (6-463): 1.53e-66: 241: 14.13
+	Hs
		244571 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		NIPBL_HUMAN (62-535): 1.22e-09: 63.9: 13.77
+	Hs
		244652 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		SRRM1_HUMAN (8-680): 2.28e-09: 62.7: 9.64
+	Hs
		1061073 BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13		NOLC1_HUMAN (1-699): 6.47e-68: 237: 100.00
+	Mm
		964613 PB1_MOUSE (27-741): 3.62e-38: 156: 12.28		TOP2A_MOUSE (6-368): 7.3e-51: 194: 16.17
+	Hs
		1061066 BRD9_HUMAN (58-237): 2.5e-24: 110: 19.34		NOLC1_HUMAN (1-699): 6.47e-68: 237: 100.00
+	Hs
		508967 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44
+	Hs
		1222852 BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13		SRRM1_HUMAN (8-680): 2.28e-09: 62.7: 9.64