HitPredict

Interactor 1: BRD2 (P25440)
Bromodomain-containing protein 2 (O27.1.1)
Gene: BRD2

Interactor 2: DHX40 (Q8IX18)
Probable ATP-dependent RNA helicase DHX40 (EC 3.6.4.13) (DEAH box protein 40) (Protein PAD)
Gene: DHX40

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 801 Hs			1 779
+	Hs
		631533 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		PRP16_HUMAN (2-778): 0: 752: 34.78
+	Hs
		1067075 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		PRP16_HUMAN (2-778): 0: 752: 34.78
+	Hs
		1123376 BRDT_HUMAN (48-763): 4.45e-106: 349: 45.39		DHX40_HUMAN (1-779): 0: 782: 100.00
+	Hs
		244643 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		DHX40_HUMAN (1-779): 0: 782: 100.00
+	Hs
		244720 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		PRP16_HUMAN (2-778): 0: 752: 34.78
+	Hs
		195282 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		DHX15_HUMAN (25-728): 0: 714: 36.28
+	Hs
		224734 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		DHX16_HUMAN (12-723): 0: 698: 37.68
+	Hs
		244341 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		DHX9_HUMAN (5-773): 0: 622: 22.49
+	Hs
		998933 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		PRP16_HUMAN (2-778): 0: 752: 34.78
+	Hs
		1220290 BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13		DHX40_HUMAN (1-779): 0: 782: 100.00
+	Hs
		999085 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		DHX36_HUMAN (6-776): 0: 737: 23.99
+	Hs
		195410 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		DHX15_HUMAN (25-728): 0: 714: 36.28
+	At
		1105309 GCN5_ARATH (351-449): 7.8e-33: 136: 37.62		DEAH5_ARATH (17-738): 0: 733: 39.47
+	Hs
		1329671 BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13		DHX36_HUMAN (6-776): 0: 737: 23.99
+	Hs
		224782 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		DHX16_HUMAN (12-723): 0: 698: 37.68
+	Sc
		859417 GCN5_YEAST (275-456): 2.99e-40: 155: 26.63		PRP43_YEAST (9-732): 0: 695: 36.33
+	Hs
		195555 BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13		DHX15_HUMAN (25-728): 0: 714: 36.28
+	Hs
		224848 BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13		DHX16_HUMAN (12-723): 0: 698: 37.68
+	Hs
		994129 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		DHX9_HUMAN (5-773): 0: 622: 22.49
+	Hs
		994351 BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13		DHX9_HUMAN (5-773): 0: 622: 22.49